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- ******************
- * recA signature *
- ******************
-
- The bacterial recA protein [1,2,3] is essential for homologous recombination.
- RecA has many functions: it binds to single- and double-stranded DNA, it binds
- and hydrolyzes ATP, it is also a recombinase and, finally, it interacts with
- lexA causing its activation and leading to its autocatalytic cleavage.
-
- RecA is a protein of about 350 amino-acid residues. Its sequence is very well
- conserved among bacterial and cyanobacterial species. As a signature pattern,
- we selected the best conserved region, a nonapeptide located in the middle of
- the sequence.
-
- -Consensus pattern: A-L-K-F-[FY]-[STA]-[STAD]-[VM]-R
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: NONE.
- -Last update: June 1994 / Pattern and text revised.
-
- [ 1] Smith K.C., Wang T.-C. V.
- BioEssays 10:12-16(1989).
- [ 2] Miller R.V., Kokjohn T.A.
- Annu. Rev. Microbiol. 44:365-394(1990).
- [ 3] Lloyd A.T., Sharp P.M.
- J. Mol. Evol. 37:399-407(1993).
-